apceth™-301 are genetically engineered MSC which express a potent “cocktail” of proinflammatory cytokines that locally activates the patient’s immune system to eradicate cancer cells.

apceth™-301 stimulates tumor immune response to recognize and destroy cancer cells by:

  • increasing IFN-γ production,
  • activating macrophages and NK-cells,
  • activating T-cells,
  • promoting long term antitumor immunity similar to cancer vaccine.

apceth™-301 is currently being developed for Glioblastoma multiforme, as well as for other solid tumors.

apceth™-301 has also shown promising synergetic effects when combined to CAR-T cell therapies.

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